personalization of CV - curriculum vitae

There's no one single answer or one single CV that fit every possible work You can apply. Is not impossible to send a generic CV all around. But Human Resource representative are used to recognized that attitude and the trash will get you CV asap.
If you show them that you don't care enough to have a personal curriculum vitae focused on that specific work position they will not risk to enroll a careless worker. A serious employer ask to you your best in any moment. It will push you to grow.
TAKE CARE OF YOUR WORKERS AND THEY WILL TAKE CARE OF YOUR BUSINESS -Sir Richard Branson.
If your Boss is not enough serious and accept lazy careless worker his enterprise will going to face failure. It will be only question of time.
Show to Your employer that You are serious, and that you seek a serious Leader, more then a boss.
You will have to rely on him maybe for all your future working life. They test You. You test them.
In the CV you show your skills, but only if related to the role you are applying. Be a python programmer is not useful to apply as a company car driver...